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pentobarbital will minimize the extent or influence of maraviroc by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
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pentobarbital will lessen the level or influence of siponimod by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of siponimod having a drug that triggers moderate CYP2C9 as well as a average or potent CYP3A4 inducer will not be suggested.
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pentobarbital will lessen the extent or effect of fosphenytoin by impacting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Monitor.
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pentobarbital will minimize the extent or impact of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. The efficacy of hormonal contraceptives may be decreased.
There won't be any facts on pregnancy exposures in primates comparable to periods ahead of the 3rd trimester in people.
pentobarbital will lessen the extent or result of elbasvir/grazoprevir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic impact of elbasvir/grazoprevir could be lowered if coadministered with robust CYP3A inducers and it is as a result contraindicated.